My Research

Research and publications

The progress we have made in treating autoimmune and inflammatory diseases over the last 20 to 30 years is driven entirely by research. Behind every modern treatment available today is a deep commitment to uncovering how these complex conditions operate at a cellular level.

During my time at the University of Washington, my research focused on the pivotal role neutrophils play in autoimmune conditions. Using specialized techniques like electron and immunofluorescence microscopy, I worked to visualize and map cellular interactions to help advance our understanding of inflammatory disease mechanisms.

Neela Moadab standing beside a research poster on PAD4 and the myosin-9 motor complex

Publications

Published under the name Fatemeh Moadab, most recent first.

2026

  1. T and B cells recognize splicing-derived neutrophil neoantigens in lupus
    Najjar R, Wang X, Shaikh F, Wang N, Le E, An J, Pourshamsi M, Mustelin C, Moadab F, Mirabile-Brightman S, Montero L, Zavala KS, Gureghian V, Cervantes G, Van den Bogaerde SJ, Adhikari S, Pogorelyy MV, Thomas PG, Schoenberger SP, Mustelin T
    Nature. Published online October 28, 2026

2025

  1. Type I interferons increase expression of endogenous retrovirus K102 and envelope protein in myeloid cells from patients with autoimmune disease
    Le E, Moadab F, Wang X, Najjar R, Bays A, Hastie KM, Shek J, Saphire EO, Mustelin T
    Mobile DNA. 2025;16(1):36
  2. Human endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM
    Shek J, Sun C, Wilson EM, Moadab F, Hastie KM, Rajamanickam RR, Penalosa PJ, Harkins SS, Parekh D, Hariharan C, Zyla DS, Yu C, Shaffer KCL, Lewis VI, Avalos RD, Mustelin T, Saphire EO
    Science Advances. 2025;11(35):eady8168
  3. Association of protein arginine deiminase 4 with the myosin-9 motor complex
    Wang X, Moadab F, Shaikh F, An J, Mustelin C, Le E, Van der Bogaerde S, Najjar R, Mustelin T
    Journal of Biological Chemistry. 2025;301(9):110513
  4. Interferons and cytokines induce transcriptional activation of the long-interspersed element-1 in myeloid cells from autoimmune patients
    Le E, Moadab F, Wang X, Najjar R, Van den Bogaerde SJ, Bays A, LaCava J, Mustelin T
    European Journal of Immunology. 2025;55(3):e2451351

2024

  1. Prevalence and contributing factors of metabolic syndrome in rheumatoid arthritis patients
    Bagheri-Hosseinabadi Z, Moadab F, Abbasifard M
    BMC Endocrine Disorders. 2024;24(1):140
  2. Evidence of membranolytic targeting and intracellular citrullination in neutrophils isolated from patients with rheumatoid arthritis
    Moadab F, Wang X, Le E, Gazitt T, Najjar R, Nelson JL, Joshua V, Malmström V, Elkon K, Grönwall C, Mustelin T
    Scientific Reports (Nature Portfolio). 2024;14(1):15511
  3. Subcellular location of L1 retrotransposon-encoded ORF1p, reverse transcription products, and DNA sensors in lupus granulocytes
    Moadab F, Sohrabi S, Wang X, Najjar R, Wolters JC, Jiang H, Miao W, Romero D, Zaller DM, Tran M, Bays A, Taylor MS, Kapeller R, LaCava J, Mustelin T
    Mobile DNA. 2024;15(1):14

2023

  1. Efferocytosis: a double-edged sword in microbial immunity
    Mohammad-Rafiei F, Moadab F, Mahmoudi A, Navashenaq JG, Gheibihayat SM
    Archives of Microbiology. 2023;205(12):370
  2. Argonaute, vault, and ribosomal proteins targeted by autoantibodies in systemic lupus erythematosus
    Moadab F, Wang X, Najjar R, Ukadike KC, Hu S, Hulett T, Bengtsson AA, Lood C, Mustelin T
    The Journal of Rheumatology. 2023;50(9):1136-1144
  3. The prevalence and contributing risk factors of coronavirus disease 2019 infection in patients with metabolic syndrome
    Bagheri-Hosseinabadi Z, Moadab F, Amiri A, Abbasifard M
    BMC Endocrine Disorders. 2023;23(1):100
  4. Immunometabolism dysfunction in the pathophysiology and treatment of rheumatoid arthritis
    Masoumi M, Hashemi N, Moadab F, Didehdar M, Farahani R, Khorramdelazad H, Sahebkar A, Johnston TP, Karami J
    Current Medicinal Chemistry. 2023;30(27):3119-3136

2022

  1. MicroRNAs and efferocytosis: implications for diagnosis and therapy
    Mahmoudi A, Moadab F, Safdarian E, Navashenaq JG, Rezaee M, Gheibihayat SM
    Mini Reviews in Medicinal Chemistry. 2022;22(20):2641-2660

2021

  1. CD47 functionalization of nanoparticles as a poly(ethylene glycol) alternative: a novel approach to improve drug delivery
    Vandchali NR, Moadab F, Taghizadeh E, Tajbakhsh A, Gheibihayat SM
    Current Drug Targets. 2021;22(15):1750-1759
  2. Role of CCL2/CCR2 axis in the immunopathogenesis of rheumatoid arthritis: latest evidence and therapeutic approaches
    Moadab F, Khorramdelazad H, Abbasifard M
    Life Sciences. 2021;269:119034